Jones, the 2016 Indy Lights champion with Carlin, spent his rookie IndyCar season with Coyne before moving to Chip Ganassi Racing in 2018.
The following year he moved to Ed Carpenter Racing to compete in the road/street courses plus the Indy 500 in 2019, but Carpenter released both Jones and team-mate Spencer Pigot at the end of the season, replacing them with Rinus VeeKay and Conor Daly.
Now Jones, who has scored three podium finishes in IndyCar including third for Coyne in his first Indy 500, returns to open-wheel racing in the #18 Team SealMaster-Dale Coyne Racing with Vasser Sullivan Honda.
Dubai-born Briton Jones said: “I’m really excited to join the Coyne Vasser Sullivan team for the 2021 IndyCar season. I started my IndyCar career with Dale and the combination of Coyne, Vasser Sullivan is a proven team over the last 3 seasons.
“I’m pumped for the opportunity to drive the #18 SealMaster machine and represent the SealMaster franchisees across the country. This really is the perfect opportunity.”
“We’re very happy to have Ed Jones back with us and back in IndyCar this season,” said Coyne. “We were sad to see him leave after his first time with us but we’ve kept in touch since.
“Ed had a great rookie season at DCR in 2017, which included our best finish of third at the Indianapolis 500.
“Now with DCVS, we hope to continue where we left off with him and look forward to a strong season.”
Co-owner Sullivan, added: “We’re full steam ahead having Ed Jones join us, and taking over the driver responsibilities for the #18 Team SealMaster machine.
“Ed has had some big moments in IndyCar, and we expect you’ll see some big moments with us together in 2021.”